BIOL 666 Mammalian Toxicology

This course provides a background in principles of toxicology in mammalian systems. It is an alternative to Environmental Toxicology, EEOS 635, as a core requirement for the Molecular, Cellular, and Organismal Biology doctoral track. Coverage includes: basic concepts of poisons and their commonalities with drugs and hormones ;toxicant exposure routes, uptake, sites and mechanisms of action, storage, metabolism, activation, and clearance; toxicant roles in carcinogenesis, development, endocrine, and reproductive functions; roles of diet, lifestyle, and concurrent exposures; methods of toxicant evaluation emphasizing multi-generation and high-throughput testing; and environmental and medical implications of toxicant/toxin expores on individual health. Students taking this course should have already completed general chemistry and organic chemistry, general biology and one advanced course in cell biology, biochemistry, or physiology.

Prerequisite(s): BIOL GRAD

3 Credit(s)